## Abstract Typically, the role of corticosterone (B) in metamorphosis is considered secondary to that of thyroid hormone, with B having only enhancing effects. In the current study, we demonstrate that the relationship between the thyroid hormones and B is much more complex and that thyroxine (T~4
Presence of thyroid hormones in ascidian larvae and their involvement in metamorphosis
β Scribed by Patricolo, Eleonora ;Cammarata, Matteo ;D?Agati, Paolo
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 453 KB
- Volume
- 290
- Category
- Article
- ISSN
- 0022-104X
- DOI
- 10.1002/jez.1084
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β¦ Synopsis
Abstract
In this study we investigated the presence and localization of thyroxine in Ciona intestinalis larvae and its involvement in metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown. In vivo treatment of swimming larvae with exogenous Lβthyroxine and thiourea, and in vitro experiments utilizing high performance liquid chromatography, radioimmunoassay, and immunoperoxidase staining demonstrate the presence of thyroxine at the larval stage. This suggests that this hormone may participate in the control of metamorphosis and thus play a different role from that observed in adults. J. Exp. Zool. 290:426β430, 2001. Β© 2001 WileyβLiss, Inc.
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