Malignant mesotheliomas (MMs) are pleural-, pericardial-, or peritoneal-based neoplasms usually associated with asbestos exposure. Mesothelial cells are biphasic and may give rise to epithelial and sarcomatous MMs. In addition, benign or atypical proliferations of mesothelial cells may occur in resp
Presence of simian virus 40 sequences in malignant pleural, peritoneal and noninvasive mesotheliomas
โ Scribed by Narayan Shivapurkar; Thorsten Wiethege; Ignacio I. Wistuba; Sara Milchgrub; Klaus-Michael Muller; Adi F. Gazdar
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 103 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Pleural and pulmonary malignancies are usually associated with well-known carcinogen exposure. Recently, the presence of simian virus 40 (SV40)-like DNA sequences has been detected in brain and bone-related human cancers and in pleural mesothelioma. In order to determine whether SV40-like DNA sequen
SV40 DNA sequences have been found in human tumors, such as mesotheliomas, ependymomas, and bone tumors, suggesting that SV40 may be involved in their etiology. The FOS oncogene could play an important role in bone development because SV40 is able to induce FOS in cell culture. In this study, the pr