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Presence of phase I and phase II drug metabolizing enzymes in cultured human foetal hepatocytes

✍ Scribed by André Guillouzo; Jean F. Le Bigot; Christiane Guguen-Guillouzo; Jean R. Kiechel

Book ID
115776486
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
777 KB
Volume
31
Category
Article
ISSN
0006-2952

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Tissue expression of drug-metabolizing enzymes influences susceptibility to drugs and carcinogens. Because the biliary epithelium, exposed to bile-borne chemicals, may give rise to drug-induced cholangiopathies and to cholangiocarcinomas, we determined the pattern of expression of drug-metabolizing