Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia
β Scribed by Staffas, A.; Zeller, B.; Kanduri, M.; Hovland, R.; Rosenquist, R.; Ommen, H. B.; Abrahamsson, J.; Forestier, E.; Jahnukainen, K.; Jonsson, O. G.
- Book ID
- 111969714
- Publisher
- American Society of Hematology
- Year
- 2011
- Tongue
- English
- Weight
- 365 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0006-4971
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## Abstract Elderly acute myeloid leukaemia (AML) patients have a dismal prognosis due to biological features of disease in itself and to presence of comorbidities. Aim of this study was to evaluate the prognostic impact of comorbidity prognostic score systems applied in our population of patients.
## Abstract Expression of __BAALC__, __ERG__, and __MN1__ is associated with outcome in normal karyotype acute myeloid leukemia (AML). In this study, the expression of these markers and of __EVI1__ and __CDKN1B__ was determined using oligonucleotide microarrays in 286 AML comprising all cytogenetic