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Presence of a receptor for albumin on individual hbsag polypeptides and on hbsag produced by a hepatoma cell line

✍ Scribed by Irina Lonescu-Matiu; Yanuario Sanchez; F. Blaine Hollinger; Joseph L Melnick; Gordon R. Dreesman

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 274 KB
Volume: 6
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890060211

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✦ Synopsis

Abstract

The receptors for polymerized (P) human (Hu) serum albumin (SA) present on intact hepatitis B surface antigen (HBsAg) have been shown to be associated with the major HBsAg polypeptides, as well as HBsAg produced in vitro by a hepatoma cell line. These observations demonstrate that the albumin receptors are virus‐specific.

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Presence of receptors for polymerized al

Presence of receptors for polymerized albumin in HBsAg-containing hepatocytes and hepatoma cell line

✍ Swan N. Thung; Michael A. Gerber 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 562 KB

Recent evidence suggests that hepatitis B virions (HBV) and HBsAg particles contain receptors for polymerized human serum albumin (pHSA). We studied, by immunohistochemical techniques, the relationship between HBsAg and pHSA receptors in liver tissue from eight patients with chronic HBV infection an