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Presence of a herpes simplex virus DNA fragment in an L cell clone obtained after infection with irradiated herpes simplex virus 1

✍ Scribed by Edmundo Kraiselburd; L. Patrick Gage; Arthur Weissbach

Book ID
119443372
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
897 KB
Volume
97
Category
Article
ISSN
0022-2836

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## Abstract To analyze the site of integration of the herpes simplex virus type 1 (HSV‐1) thymidine kinase (TK) gene in biochemically transformed human cells, TK‐HeLa‐(BU25) cells were transformed to the TK^+^ phenotype by a cloned, 2 kbp Pvull fragment of HSV‐1 DNA. The transformed cells [HeLa(BU2