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Presence of a carcinoma-associated antigen(s) in the spent chemically defined medium of a human colon carcinoma cell line

✍ Scribed by Dr. Darwin O. Chee; Rishab K. Gupta; Donald L. Morton


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
402 KB
Volume
13
Category
Article
ISSN
0022-4790

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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) Ξ±, Ξ², and Ξ³ chains. The Ξ² and Ξ³ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2RΞ± lacks