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Preparative Enzymatic Synthesis of Glucuronides of Zearalenone and Five of Its Metabolites

✍ Scribed by Stevenson, David E.; Hansen, Richard P.; Loader, Jared I.; Jensen, Dwayne J.; Cooney, Janine M.; Wilkins, Alistair L.; Miles, Christopher O.

Book ID
121719725
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
738 KB
Volume
56
Category
Article
ISSN
0021-8561

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Glucuronidation of zearalenone, zeranol
Glucuronidation of zearalenone, zeranol and four metabolites in vitro: Formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms
✍ Erika Pfeiffer; Andreas Hildebrand; Hannes Mikula; Manfred Metzler πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 223 KB

## Abstract Glucuronidation constitutes an important pathway in the phase II metabolism of the mycotoxin zearalenone (ZEN) and the growth promotor α‐zearalanol (α‐ZAL, zeranol), but the enzymology of their formation is yet unknown. In the present study, ZEN, α‐ZAL and four of their major phase I me