𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Preparative conversion of chloralamides to 2,5-diaryl-3a,6a-dihydro-[1,3]thiazolo[4,5-d][1,3]thiazoles with the Lawesson reagent

✍ Scribed by Bogdan A. Demydchuk; Vladimir S. Brovarets; Alexander N. Vasilenko; Boris S. Drach

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
98 KB
Volume
19
Category
Article
ISSN
1042-7163

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Based on readily available chloralamides, a preparative method for the synthesis of hitherto unknown 2,5‐diaryl‐3a,6a‐dihydro[1,3]thiazolo[4,5‐d][1,3]thiazoles with the Lawesson reagent has been elaborated. Β© 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:677–681, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20493

πŸ“œ SIMILAR VOLUMES

Thionation of N-(Ο‰-Halogenoalkyl)-Substi
Thionation of N-(Ο‰-Halogenoalkyl)-Substituted Amides with Lawesson's Reagent: Facile Synthesis of 4,5-Dihydro-1,3-thiazoles and 5,6-Dihydro-4H-1,3-thiazines
✍ Yasuhiro Kodama; Mayuko Ori; Takehiko Nishio πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 German βš– 88 KB

The thionation and cyclization of N-(w-halogenoalkyl)-substituted amides (and related compounds) with Lawessons reagent (LR 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide) has been investigated. Treatment of the amides 1 with LR gave the corresponding thioamides 2 in moderate to