Preparative Chromatography, Second Edition

• Year: 2012
• Tongue: English
• Leaves: 561
• Category: Library

✦ Synopsis

Completely revised to reflect the developments in this fast-changing field, this new edition features 35 % new content. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography.
Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes.
Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.

✦ Table of Contents

Content:
Chapter 1 Introduction (pages 1–6): Prof. Dr.?Ing. Henner Schmidt?Traub and Reinhard Ditz
Chapter 2 Fundamentals and General Terminology (pages 7–46): Prof. Dr.?Ing. Andreas Seidel?Morgenstern, Dr. Michael Schulte and Achim Epping
Chapter 3 Stationary Phases and Chromatographic Systems (pages 47–198): Dr. Michael Schulte, Matthias Johnck, Romas Skudas, Klaus K. Unger, Cedric du Fresne von Hohenesche, Wolfgang Wewers, Jules Dingenen and Joachim Kinkel
Chapter 4 Chromatography Equipment: Engineering and Operation (pages 199–271): Abdelaziz Toumi, Jules Dingenen, Joel Genolet, Olivier Ludemann?Hombourger, Andre Kiesewetter, Martin Krahe, Michele Morelli, Prof. Dr.?Ing. Henner Schmidt?Traub, Andreas Stein and Eric Valery
Chapter 5 Process Concepts (pages 273–320): Malte Kaspereit, Dr. Michael Schulte, Klaus Wekenborg and Wolfgang Wewers
Chapter 6 Modeling and Model Parameters (pages 321–424): Prof. Dr.?Ing. Andreas Seidel?Morgenstern, Prof. Dr.?Ing. Henner Schmidt?Traub, Mirko Michel, Achim Epping and Andreas Jupke
Chapter 7 Model?Based Design, Optimization, and Control (pages 425–518): Prof. Dr.?Ing. Henner Schmidt?Traub, Malte Kaspereit, Sebastian Engell, Arthur Susanto, Achim Epping and Andreas Jupke