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Preparation of α-Bromo- and α-Chlorocarboxylic Acids from α-Amino Acids

✍ Scribed by George A. Olah; Joseph Shih; G. K. Surya Prakash

Publisher: John Wiley and Sons
Year: 1983
Tongue: German
Weight: 146 KB
Volume: 66
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19830660404

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✦ Synopsis

Abstract

Diazotization of α‐amino acids in 48:52 (w/w) hydrogen fluoride/pyridine along with excess of potassium halide results in the corresponding α‐halocarboxylic acids in good to excellent yields (Table 1 and 2).

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