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Preparation of Water-Soluble Compounds by Covalent Attachment of Solubilizing Moieties

โœ Scribed by Camille G. Wermuth; Jeal de La Fontaine

Book ID
101955127
Publisher
John Wiley and Sons
Year
2004
Weight
53 KB
Volume
35
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

๐Ÿ“œ SIMILAR VOLUMES

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Permeability assessment of poorly water-soluble compounds under solubilizing conditions: The reciprocal permeability approach
โœ Kasiram Katneni; Susan A. Charman; Christopher J.H. Porter ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 201 KB

The objective of this study was to develop a general method to assess the intestinal permeability of poorly water-soluble drugs where low-aqueous drug solubility requires conduct of experiments under solubilizing experimental conditions. The permeability (Papp) of diazepam (DIA) was assessed across