Preparation of thermo-responsive and injectable hydrogels based on hyaluronic acid and poly(N-isopropylacrylamide) and their drug release behaviors
β Scribed by Dong In Ha; Sang Bong Lee; Moo Sang Chong; Young Moo Lee; So Yeon Kim; Young Hoon Park
- Publisher
- The Polymer Society of Korea
- Year
- 2006
- Tongue
- English
- Weight
- 313 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1598-5032
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π SIMILAR VOLUMES
## Abstract To achieve the injectable hydrogel system in order to improve bone regeneration by locally delivering a protein drug including bone morphogenetic proteins, thermoβresponsive injectable hydrogels composed of __N__βisopropylacrylamide (NIPAAm) and vinyl phosphonic acid (VPAc) were prepare
Interpenetrating polymer networks (IPNs) of poly(N-isopropylacrylamide)/ polyurethane (PNIPAAm/PU) and poly(N-isopropylacrylamide)/poly(acrylic acid) (PNI-PAAm/PAA) were synthesized to investigate the swelling and drug releasing behavior. The presence of urethane network in PNIPAAm/PU IPNs improved