𝔖 Bobbio Scriptorium
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Preparation of specific antisera toDrosophilaacid phosphatase without rigorous protein purification

✍ Scribed by Norman Arnheim; Ross MacIntyre


Book ID
104784243
Publisher
Springer
Year
1976
Tongue
English
Weight
334 KB
Volume
14
Category
Article
ISSN
0006-2928

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✦ Synopsis


Extracts from an acid phosphatase CRM-null mutant of Drosophila melanogaster were used to eliminate contaminating antibodies in a nonspeeific preparation of anti-aeid phosphatase serum. This method of producing specific antisera makes unnecessary the rigorous purification of an antigen prior to immunization attempts in those cases where CRM-null mutants of the antigen are available. Antisera so prepared could be used for a wide variety of purposes.