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Preparation of some substituted imidazolidine-2,4-diones

โœ Scribed by J. Sam; E. B. McLaurin; R. M. Shafik

Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
240 KB
Volume
58
Category
Article
ISSN
0022-3549

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A chiral center in a drug molecule increases the complexity of synthetic, metabolic, pharmacological, and clinical studies, an additional problem being a possible lack of configurational stability. Here, we report detailed kinetic and mechanistic studies on the deuteration and racemization of seven