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Preparation of pyrrolin-2-ones and 4,5-dihydrodipyrrin-1-ones by oxidation of α-formylpyrroles and α-formyldipyrromethanes with hydrogen peroxide

✍ Scribed by Clotilde Pichon-Santander; A.Ian Scott


Book ID
108379682
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
231 KB
Volume
41
Category
Article
ISSN
0040-4039

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Reactions of 4-oxoalkanoic acids. III. S
✍ Dr. Christine Wedler; Dr. sc. nat. Burkhard Costisella; Prof. Dr. sc. nat. Hans 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 385 KB

## Abstract A re‐examination of the reaction of α‐angelica lactone with methylamine in water confirmed that 5‐hydroxy‐1,5‐dimethylpyrrolidin‐2‐one (5) was formed almost quantitatively in a very fast reaction. Dehydration of this compound by vacuum distillation, however, unexpectedly afforded 1‐meth