✦ LIBER ✦
Preparation of protein-loaded-PLGA microspheres by an emulsion/solvent evaporation process employing LTCC micromixers
✍ Scribed by R.M. Ribeiro-Costa; Márcio Rodrigues da Cunha; M.R. Gongora-Rubio; P. Michaluart-Júnior; M.I. Ré
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 639 KB
- Volume
- 190
- Category
- Article
- ISSN
- 0032-5910
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✦ Synopsis
This study presents the possibilities offered by microfluidic structures for the production of polymeric microspheres, using a process based upon the production of an emulsion. LTCC (Low Temperature Co-fired Ceramics) micromixers have been used for the preparation of polymeric microspheres. The effect of the geometry of the micromixers has been studied, with a specific focus on the size of the microspheres, as well as the control release properties of a model protein loaded within these microspheres.