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Preparation of pH-sensitive hydrogel microspheres of poly(acrylamide-co-methacrylic acid) with sharp pH–volume transition

✍ Scribed by Henmei Ni; Haruma Kawaguchi; Takeshi Endo

Publisher
Springer
Year
2007
Weight
182 KB
Volume
285
Category
Article
ISSN
0340-255X

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## Abstract It was found that the upper critical solution temperature (UCST) of poly(acrylic acid‐__co__‐acrylamide) hydrogel decreases with increase in pH. The UCST of samples equilibrated in a buffer at pH 2.5 was 33.7 °C, whereas it shifted to below 0 °C when swollen in buffers above pH 10. FT‐I