PREPARATION OF OPTICALLY ACTIVE NEW MERCAPTO CHIRAL AUXILIARIES DERIVED FROM CAMPHOR
β Scribed by Lee, Dong-Sheng; Hung, Shung-Ming; Lai, Ming-Chun; Chu, Han-Yang; Yang, Teng-Kuei
- Book ID
- 120991322
- Publisher
- Taylor and Francis Group
- Year
- 1993
- Tongue
- English
- Weight
- 409 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0030-4948
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π SIMILAR VOLUMES
The synthesis of chiral aminoalcohols 4 derived from (S)-tryptophan is described, by reaction of the protected amino acid 3 with various Grignard reagents. The aminoalcohols were transformed into the corresponding oxazolidin-2-ones 2 and acylated with 2-butenoyl chloride and 2-hexenoyl chloride, aff
The synthesis of a variety of enantiomerically pure chiral auxiliaries based on (S)-proline and bearing sterically demanding side chains at the pyrrolidine moiety, such as the secondary amines (s)-2,5 and 2 and the hydrazines (S)-a, is described on a molar scale. As key step, the Grignard or RLi add