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Preparation of Nε-(3-hydroxy-16-oxoestra-1,3,5(10)-trien-17β-YL)-l-lysine, 16α-hydroxyestrone-lysing adduct, via heyns rearrangement

✍ Scribed by Shinichi Miyairi; Takanori Ichikawa; Toshio Nambara


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
135 KB
Volume
32
Category
Article
ISSN
0040-4039

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✦ Synopsis


Preparation of a stable covalent aaiiuctfrom 16cMydroxyestrone with the e-amino group of lysine via two step reactions involving Schiff base formation followed by Heyns rearrangement is described.