Preparation of methyl 10-oxo-15S-hydroxyprosta-5E,13Z-dienoate
β Scribed by Henry C. Arndt; Cynthia Rajani
- Book ID
- 104220842
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 167 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The synthesis of methyl lo-oxo-15S-hydroxyprosta-5E,l3Z_dienoate is described.
π SIMILAR VOLUMES
The syntheses and reactions of two epoxyketoacids (methyl (Z)-9,10-epoxy-13-oxo-(E)-II-octadecenoate (IV) and methyl (E)-9,10-epoxy-13-oxo-(E)-ll-octadecenoate (V)) are described. The synthetic method is based on the stereoselective oxidation of linoleic acid by soybean lipoxygenase to produce the c
3Z,6Z,9Z,12E)-Pentadecatetraenal, a common intermediate in the synthesis of methyl A l7t EPA and methyl A I9t DHA, was obtained by copper(I)-catalyzed coupling between the Grignard reagent of I, 1-diethoxy-3-butyne and (Z, E)l-bromo-5,8-undecadien-2-yne followed by semi-hydrogenation of the resultin