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Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying: effect of protective agents (polyethyleneimine and sugars) on the stability of DNA

โœ Scribed by Jung-hua Steven Kuo; Robin Hwang


Book ID
111769031
Publisher
Pharmaceutical Press
Year
2004
Tongue
English
Weight
432 KB
Volume
56
Category
Article
ISSN
2042-7158

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Preparation of dry powder dispersions fo
โœ P. C. Seville; I. W. Kellaway; J. C. Birchall ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 514 KB

## Abstract ## Background Dry powder dispersion devices offer potential for delivering therapeutic macromolecules to the pulmonary epithelia. Previously, freezeโ€drying (lyophilisation) has been the accepted method for preparing dried formulations of proteins and nonโ€viral gene vectors despite the