2-Phenylsulphonyl cyclic ethers undergo facile displacement of the sulphonyl group by alcohols, in the presence of magnesium bromide etherate and sodium bicarbonate in tetrahydrofuran, to give good yields of the corresponding acetals. The preparation of tetrahydro-pyran and -furan ethers typically
β¦ LIBER β¦
Preparation of cyclic ether acetals from 2-benzenesulphonylderivatives: a new mild glycosidation procedure
β Scribed by Dearg S. Brown; Steven V. Ley; Sadie Vile
- Book ID
- 104216725
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 224 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Several alcohols ranging from hindered to those containing chemically sensitive groups react with 2-benzenesulphonyl cyclic ethers in the presence of magnesium bromide etherate and sodium bicarbonate to give good yields of the corresponding acetals.
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