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Preparation of crystalline L-α-glycerophosphoryl-choline-cadmium chloride adduct from commercial egg lecithin

✍ Scribed by Jaswinder Singh Chadha


Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
216 KB
Volume
4
Category
Article
ISSN
0009-3084

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✦ Synopsis


Preparation of crystalline L-a-GPC/CdCI 2 complex from an average sample of commercial egg lecithin containing phosphatidylethanolamine (P.E.), sphingomyelin and other lipids is described. The method has been used for preparing up to 250 g of the L-a-GPC/ CdCI 2 complex. Commercial egg lecithin is methanolysed in ether/methanol, when crude GPC containing GPE and two other impurities is precipitated. Crystalline L-<~-GPC/ CdCI2 is obtained from the crude GPC by a combination of solvent extractions and fractional crystallisation stages.