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Preparation of Cross-Linked Poly[(ε-caprolactone)-co-lactide] and Biocompatibility Studies for Tissue Engineering Materials

✍ Scribed by Hiroshi Miyasako; Kazuya Yamamoto; Aiko Nakao; Takao Aoyagi

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 425 KB
Volume: 7
Category: Article
ISSN: 1616-5187
DOI: 10.1002/mabi.200600188

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✦ Synopsis

Abstract

In this study, cross‐linked materials were prepared using the branched macromonomer with different CL/LA molar ratios, and feasibility studies for tissue engineering were carried out. The thermal and mechanical properties of these materials depended on the CL/LA compositions; however, there was no change in the wettability of each material. The HeLa cells adhesion and growth on the CL‐LA7030c were equal to that on the commercially available polystyrene dish. The protein absorption experiment using the FBS proteins revealed that the materials with well‐grown cells showed better adhesion of the proteins.

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