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Preparation of chitosan-poly(acrylic acid) nanoparticles and its solubilizing abilities for water-insoluble drugs

✍ Scribed by He, Nai-Pu; Du, Xi; Huang, Si-Kai


Book ID
122175973
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
250 KB
Volume
172
Category
Article
ISSN
0168-3659

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## Abstract Chitosan (CS) nanoparticles with different mean sizes ranging from 100 to 195 nm were prepared by ionic gelation of CS and poly(acrylic acid) (PAA). Variations in the final solution pH value and CS : PAA volume ratio were examined systematically for their effects on nanoparticle size, i