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Preparation of Chiral Multifunctional Thiourea–Phosphanes and Synthesis of Chiral Allylic Phosphites and Phosphane Oxides through Asymmetric Allylic Substitution Reactions of Morita–Baylis–Hillman Carbonates

✍ Scribed by Hong-Ping Deng; Min Shi


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
528 KB
Volume
2012
Category
Article
ISSN
1434-193X

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## Abstract A series of multifunctional, chiral amide–phosphane organocatalysts have been designed and synthesized for the allylic substitution of Morita–Baylis–Hillman (MBH) acetate with 2‐trimethylsilyloxyfuran for butenolide synthesis. This reaction was achieved in good to excellent yield (42–98