This study was conducted to provide data on the pharmacokinetics of [ 14 C]metosulam (N-[2,6-dichloro-3-methylphenyl]-5,7-dimethoxy-1,2,4-triazolo-[1,5a]-[pyrimidine-2-sulfonamide). Groups of male Sprague-Dawley rats, CD-1 mice and Beagle dogs were given a single oral gavage dose of 100 mg [ 14 C]me
Preparation of carbon-14 labeled N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide
โ Scribed by L. H. McKendry
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- French
- Weight
- 546 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2135
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## Abstract magnified image The 7โarylโ4,7โdihydro[1,2,4]triazolo[1,5โ__a__]pyrimidines **1a**, **1b**, **1c** can undergo addition of hydrazine to the enamine double bond leading to hydrazine derivatives of tetrahydrotriazolopyrimidines **2a**, **2b**, **2c**; the process is usually accompanied by
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
## Abstract magnified image The condensation of 5โaminoโ4โphenylโ1,2,3โtriazole (**1**) with chalcones **2aโe** or 3โdimethylaminoโpropiophenone (**4f**) leads to the 6,7โdihydroโ(1,2,3)โtriazolo[1,5โ__a__]pyrimidines **3aโf.** The equilibrium of **3** and the tautomeric 4,7โdihydroโ(1,2,3)โtriazo