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Preparation of bupivacaine-loaded poly(ε-caprolactone) microspheres by spray drying: drug release studies and biocompatibility

✍ Scribed by M.D Blanco; M.V Bernardo; R.L Sastre; R Olmo; E Muñiz; J.M Teijón

Book ID
117639422
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
521 KB
Volume
55
Category
Article
ISSN
0939-6411

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Preparation, characterization, and drug release behaviors of drug nimodipine-loaded poly(ε-caprolactone)-poly(ethylene oxide)-poly(ε-caprolactone) amphiphilic triblock copolymer micelles
✍ Haixiong Ge; Yong Hu; Xiqun Jiang; Daming Cheng; Yuyan Yuan; Hong Bi; Changzheng 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB

Amphiphilic triblock copolymers, poly(epsilon-caprolactone)-poly(ethylene oxide)-poly(epsilon-caprolactone) (PCL-PEO-PCL), were synthesized by ring opening polymerization of epsilon-caprolactone initiated with the hydroxyl functional groups of poly(ethylene glycol) at both ends of the chain. The mic