✦ LIBER ✦
Preparation of bromine-77 labelled monoclonal anti-hPLAP antibody using chloramine-T
✍ Scribed by Fabienne Lambert; Guido Slegers; Patrick Goethals
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- French
- Weight
- 258 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
A tumor‐associated monoclonal antibody, named 7E8 and raised against human placental alkaline phosphatase (hPLAP), is labelled with bromine‐77 by means of chloramine‐T. The paper describes optimum radiobromination conditions resulting in 34% radiochemical yield of labelled antibody with more than 90% immunoreactivity.