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Preparation of Azacrown-Functionalized 2‘- O -Methyl Oligoribonucleotides, Potential Artificial RNases

✍ Scribed by Niittymäki, Teija; Kaukinen, Ulla; Virta, Pasi; Mikkola, Satu; Lönnberg, Harri

Book ID: 120351126
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 173 KB
Volume: 15
Category: Article
ISSN: 1043-1802
DOI: 10.1021/bc034166b

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## Abstract End‐functionalized (1→6)‐2,5‐anhydro‐3,4‐di‐__O__‐methyl‐D‐glucitols (3a–c) were synthesized by the anionic cyclopolymerization of 1,2:5,6‐dianhydro‐3,4‐di‐__O__‐methyl‐D‐mannitol (1), followed by treatment with a terminating agent such as 4‐vinylbenzyl (2a), oxetanyl (2b), and methacry