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Preparation of an affinity chromatography matrix for the selective purification of the dopamine D2 receptor from bovine striatal membranes

✍ Scribed by Margaret Clagett-Dame; Robert Schoenleber; Christine Chung; Jeffrey F. McKelvy


Book ID
115729156
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
996 KB
Volume
986
Category
Article
ISSN
0005-2736

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am