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Preparation of .alpha.-oxo amidines by the direct nucleophilic acylation of carbodiimides

✍ Scribed by Seyferth, Dietmar; Hui, Richard C.


Book ID
125477701
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
348 KB
Volume
50
Category
Article
ISSN
0022-3263

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## Formation of the S-unsubstituted, O-methyl acyl tetronic acid nucleus found in tetronasin (1) has been achieved by the direct acylation of a 3-stannyl tetronate with a variety of acid chlorides in the presence of a palladium catalyst. Funherjknctionalizanon of the tin tetronate at C-5 prior ro ac