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Preparation of Alkenyl Cyclopropanes through a Ruthenium-Catalyzed Tandem Enyne Metathesis−Cyclopropanation Sequence

✍ Scribed by Kim, Byung Gyu; Snapper, Marc L.


Book ID
126034840
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
61 KB
Volume
128
Category
Article
ISSN
0002-7863

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The reaction of fluorinated 1,6- and 1,7-enynes, containing the moiety N(PG)C(CF(3))(CO(2)R), with diazo compounds in the presence of [RuCl(cod)(Cp\*)] (cod=cycloocta-1,5-diene, Cp\*=C(5)Me(5) , PG=protecting group) as the catalyst precursor leads to the formation of fluorinated 3-azabicyclo[3.1.0]h