Preparation of [3H]N, N-dimethylaniline by microwave discharge activation of tritium gas. Absence of ring saturation

✍ Scribed by C. T. Peng; S. F. Ding; R. R. Hua

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: French
• Weight: 394 KB
• Volume: 24
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580240505

✦ Synopsis

3H]N,N-Dimethylanillne was prepared from N,N-dimethylaniline by tritium labeling by microwave discharge activation of tritium gas; the product was formed without any ring saturated side products. High specific activity and high yield were achieved by input of high microwave power to excite the plasma and by dispersion of substrate on silica-alumina pellets to increase the contact surface with tritium gas. Circulation or no circulation of tritium gas during labeling did not effect the yield or the specific activity. Dispersio supported Ni catalyst caused an increase in the specific activity of [ H],N,Ndimethylaniline than on plain silica-alumina. The lack of ring saturation in N,N-dimethylaniline in contrast to complete ring saturation in benzene and benzoic acid has been interpretated to indicate the involvement of tritium ions in addition to tritium atoms in tritium labeling.