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Preparation of 3e,4,5,6e,7,8-hexahydro[2.2]paracyclophane

โœ Scribed by Shaw-Tao Lin; Fu-May Yang; Lee-Huey Lin


Book ID
108378790
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
323 KB
Volume
53
Category
Article
ISSN
0040-4020

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The 2,3,4,4a,5, isoquinoline-7(7aH)-one ring system is prepared from a 4-arylpyridine precursor by sequential intramolecular enolate addition to a pyridinium ion, Dieckmann cyclization, and catalytic hydrogenation.