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Preparation of 17-keto(or hydroxy)-5′-alkyl(or aryl)-estra-1(10),4-dieno[3,2-b]furans

✍ Scribed by M. Stefanović; Lj. Krstić; S. Mladenović

Publisher: Elsevier Science
Year: 1971
Tongue: French
Weight: 107 KB
Volume: 12
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)97164-3

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✦ Synopsis

An increasing interest in the chemistry of heterocyclic steroids having a hetero-ring fused to the ring A of steroid nucleus (l), has provoked us to present a simple 2-step method for the synthesis of title compounds. The literature reports on the heterocyclic steroids containing furan ring attached to the ring A of steroid nucleus have been insofar spsrse (2,3). Moreover, all the published methods can be hardly used as a straightforward route for the preparation of these compounds.

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