Preparation et reactivite du derive lithie issu du dioxolanne du -ceto pentanoate de trimethylsilyle.

✍ Scribed by Jean Louis Moreau; René Couffignal

• Book ID: 104219826
• Publisher: Elsevier Science
• Year: 1982
• Tongue: French
• Weight: 203 KB
• Volume: 23
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)85816-5

✦ Synopsis

The organolithium reagent $ issued from trimethylsilyl 4,4_ethylendioxypentanoate 2 reacts with ketones ; it affords 8-hydroxy-acids 1 and B-ethylenic ketones 8. This reaction is an efficient route for carbonyl olefination. 4 also acts towards mixed carboxylic and carbonic anhydrides as a homoenolate equivalent.

Nous avons rdcemment signale' que le dioxolanne acide 2 dtait facilement accessible -