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Preparation, characterization, cytotoxicity, and mutagenicity of a pair of enantiomeric platinum(II) complexes with the potential to bind enantioselectively to DNA

✍ Scribed by Vickery, Kymberley; Bonin, Antonio M.; Fenton, Ronald R.; O'Mara, Shaun; Russell, Pamela J.; Webster, Lorraine K.; Hambley, Trevor W.


Book ID
126858598
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
754 KB
Volume
36
Category
Article
ISSN
0022-2623

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The Influence of the Axial Ligands of a
✍ Ellis, LT; Er, HM; Hambley, TW πŸ“‚ Article πŸ“… 1995 πŸ› Commonwealth Scientific and Industrial Research Or 🌐 English βš– 612 KB

The electrochemical reduction and DNA binding have been studied for a series of platinum(IV) complexes with Cl-, OH-, and carboxylate anions as the axial ligands ; [Pt(en)Cl4], [Pt(en)Cl2(OH)2], and [Pt(en)Cl2(OC(O)R)2], R = CH3, CH2CH3, CH2CH2CH3. Cathodic reduction potentials vary by more than 650