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Preparation, characterization and in vivo evaluation of 120-day poly(d,l-lactide) leuprolide microspheres

✍ Scribed by Byung H Woo; Janusz W Kostanski; Sisay Gebrekidan; Bhas A Dani; B.C Thanoo; Patrick P DeLuca

Book ID
114161347
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
662 KB
Volume
75
Category
Article
ISSN
0168-3659

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✍ Sandra Guerrero; Enriqueta MuΓ±Γ­z; CΓ©sar TeijΓ³n; Rosa Olmo; JosΓ© M. TeijΓ³n; M. Do πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 629 KB

Ketotifen (KT) was encapsulated into poly(D,L-lactide) (PLA) and poly(D,Llactide-co-glycolide) (PLGA 50/50) by spray-drying to investigate the use of biodegradable drug-loaded microspheres as delivery systems in the intraperitoneal cavity. Ketotifen stability was evaluated by HPLC, and degradation w