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Preparation, characteristics and biocompatibility of chitosan-based thermosensitive hydrogels as drug delivery system

✍ Scribed by Hui Yun Zhou; Xi Guang Chen; Cheng Sheng Liu


Book ID
118473627
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
88 KB
Volume
136
Category
Article
ISSN
0168-1656

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A new thermosensitive hydrogel was designed and prepared by simply mixing N- [(2-hydroxy-3-trimethylammonium) propyl] chitosan chloride (HTCC) and poly(ethylene glycol) (PEG) with a small amount of a-b-glycerophosphate (a-b-GP). The optimum preparative condition was investigated, and the obtained fo