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Preparation and the in-vivo evaluation of paclitaxel liposomes for lung targeting delivery in dogs

✍ Scribed by Ling Zhao; Yun Ye; Juan Li; Yu-meng Wei


Book ID
118111434
Publisher
Pharmaceutical Press
Year
2010
Tongue
English
Weight
661 KB
Volume
63
Category
Article
ISSN
2042-7158

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✍ Javed Iqbal; Federica Sarti; Glen Perera; Andreas Bernkop-SchnΓΌrch πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 221 KB

The aim of the present study was to investigate the effect of poly(acrylic acid)-cysteine (PAA-cysteine) exhibiting a molecular mass of 100 and 250 kDa and reduced glutathione (GSH) on the absorption of the P-glycoprotein (P-gp) and cytochrome P450 (CYP450) substrate paclitaxel in vitro and in vivo.