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Preparation and reactions of alkoxy allylic zirconium reagents derived from acetals of α,β-unsaturated aldehydes: Remarkable substituent effects on regioselectivity

✍ Scribed by Hisanaka Ito; Takeo Taguchi; Yuji Hanzawa


Book ID
104214777
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
303 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis


Alkoxy allylic zirconium reagents, prepared from acet& of a,tWttsaturated a&i&y&s and "Cp$Y, react with carbonyl compounds to give 1 &diols or rhydroxy aldehyde derivatives.

Diastereoselective addition reactions of ralkoxy allylic organometallics to carbonyl compounds are an ideal means for the construction of allylic 1,2-dials, important building blocks for natural products synthesis. metals.1