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Preparation and Reactions of 11-Substituted 1,3,5(10)-Estratrienes. II. Synthesis of 19-Norhydrocortisone 1

✍ Scribed by Magerlein, Barney J.; Hogg, John A.


Book ID
126249176
Publisher
American Chemical Society
Year
1958
Tongue
English
Weight
484 KB
Volume
80
Category
Article
ISSN
0002-7863

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The Enantioselective Synthesis of 3-Meth
✍ Wolfgang Oppolzer; Kurt Bättig; Martin Petrzilka 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 German ⚖ 189 KB

## Abstract The enantiomerically pure (+)‐3‐methoxy‐1, 3, 5 (10)‐estratrien‐11, 17‐dione **11** (with __trans‐anti‐trans__ configuration) was synthesized in a highly stereocontrolled fashion from (±)‐__t__‐butyl 4‐methoxy‐1‐benzocyclobutene carboxylate **(8)** and the (+)‐carboxylic acid **6**, obt