Three solid forms of iopanoic acid were characterized by X-ray diffraction, differential scanning calorimetry, scanning electron microscopy, thermal microscopy, IR spectroscopy, and dissolution studies. X-ray analysis demonstrated that two solid forms were crystalline and that the third was amorphou
Preparation and physical characterization of forms II and III of paracetamol
β Scribed by P. Di Martino; P. Conflant; M. Drache; J. -P. Huvenne; A. -M. Guyot-Hermann
- Publisher
- Springer Netherlands
- Year
- 1997
- Tongue
- English
- Weight
- 997 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-5215
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This work reports the preparation and crystal structure of a trihydrate of paracetamol. Crystals were grown by slow cooling of an aqueous solution of paracetamol to 08C. Single-crystal X-ray diffraction shows that the trihydrate crystallizes in the orthorhombic crystal system, space group Pbca, Z ΒΌ