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Preparation and in vitro evaluation of pyridostigmine bromide microparticles

✍ Scribed by Nahed Hegazy; Müzeyyen Demirel; Yasemin Yazan

Book ID
108454099
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
127 KB
Volume
242
Category
Article
ISSN
0378-5173

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Preparation of pyridostigmine bromide la
Preparation of pyridostigmine bromide labeled with carbon-14 and tritium1
✍ J. A. Kepler; C. E. Twine; R. D. Austin 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 545 KB

## Abstract [2‐^14^C]Pyridostigmine bromide was prepared in 17.6% radiochemical yield with specific activity of 18 mCi/mmol. The reaction sequence involved preparation of 2‐furan[^14^C]carboxylic acid by carbonation of 2‐lithiofuran, followed by conversion to 2‐amino[^14^C]methyl furan by lithium a