A mixture of hydrophilic complexes is formed on the reduction (employing tin metal as a reductant) of sodium pertechnetate 99mTc in the presence of the ligand thiodiglycollic acid (TDG). When administered to rats, the mixture demonstrated a renal clearance rate marginally greater than Glomerular fil
Preparation and evaluation of99mTc-thiodiglycolic acid (TDGA) for renal function studies
β Scribed by N. Ramamoorthy; S. A. Balakrishnan; S. M. Gaitonde; P. M. Pandey; U. N. Nayak; M. C. Patel; R. B. Patel; P. Ramanathan
- Book ID
- 112723431
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 397 KB
- Volume
- 134
- Category
- Article
- ISSN
- 1588-2780
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The present study aimed at comparing two renal function tests using 99mTc-DTPA (diethylene triamine penta acetic acid) and 131I-labeled hippuran (o-hippuric acid). A mixture of 80 MBq 99mTc-DTPA and 7.4 MBq 131I-hippuran in a total volume of 1.5 ml or less was injected into an arm-vein. Both radioph
Consequent to the promising results reported with 99mTc(V)-DMSA for imaging certain types of soft tissue tumors, we have developed methods to prepare this radiopharmaceutical in three ways: from freshly prepared reagents, through the use of a two component kit and use of the standard renal DMSA kit
Studies of the chemistry of preparation of tin chelate 2.3-dimercaptosuccinic acid (DMS) complexed with 99mTc with respect to its biological properties have been made. We have varied molar ratio of reactants (DMS:Sn/II/), concentration of Sn-DMS chelate and pH of 99mTc-DMS injection solution and exa