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Preparation and evaluation of sustained-release diltiazem hydrochloride pellets

โœ Scribed by Han, Xiaopeng; Wang, Linan; Sun, Yinghua; Liu, Xiaohong; Liu, Wanjun; Du, Yuqian; Li, Lin; Sun, Jin


Book ID
122237812
Publisher
Elsevier
Year
2013
Tongue
English
Weight
528 KB
Volume
8
Category
Article
ISSN
1818-0876

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The pharmacokinetics of a new oral sustained-release diltiazem preparation (HER-SR,QD) was investigated in dogs and humans. The mean plasma diltiazem concentration in dogs after oral administration of HER-SR showed a prolonged plasma concentration and a double peak. The bioavailability of HER-SR com