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Preparation and evaluation of antibacterial activity of some new 1,2,4-triazole derivatives

✍ Scribed by W. A. A. Arafa

Publisher: Journal of Heterocyclic Chemistry
Year: 2010
Tongue: English
Weight: 209 KB
Volume: 47
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.431

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✦ Synopsis

Abstract

magnified image Cyclizations of 1,5‐diphenyl[1,2,4]triazole‐3‐carbohydrazide 1 and the thiosemicarbazide 2 (derived from 1 by addition to phenylisothiocyanate) under various conditions afforded novel biheterocyclic systems. The newly prepared compounds were screened for their antibacterial activity. The results showed that several of these compounds exhibited significant antibacterial activity. J. Heterocyclic Chem., (2010).

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