The 14-aminoacid peptide bombesin (BN) has a high affinity for the gastrin-releasing peptide receptor which is expressed by a variety of tumours. Thus, radiometal-labelled DTPA-BN derivatives are potentially useful radioligands for receptor-targeted scintigraphy and radiotherapy of BN receptor-expre
โฆ LIBER โฆ
Preparation and evaluation of a new radiolabeled bombesin analogue for diagnosis of bombesin receptor expressing tumors
โ Scribed by Erfani Mostafa; Goudarzi Mostafa; Shirmardi Seyed Pejman
- Book ID
- 118431199
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 52 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0009-9120
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Bombesin (BN) is a 14-amino-acid neuropeptide with a high affinity for the gastrin-releasing peptide receptor. This receptor has been found to be expressed in a variety of tumours, including lung, breast, prostate and pancreas. A newly synthesized BN analogue, [DTPA-Pro 1 ,Tyr 4 ]BN, was shown to be